Examinando por Autor "Castellini, Horacio V."
Mostrando 1 - 8 de 8
Resultados por página
Opciones de ordenación
Ítem Acceso Abierto Alterations of the erythrocyte membrane by in vitro action of Trichinella spiralis muscle larvae(Cambridge University Press, 2018-11-29) Ponce de León, Patricia; Bellini, Mariana; Castellini, Horacio V.; Riquelme, Bibiana DorisÍtem Acceso Abierto Application of a digital image procedure to evaluate microstructure of caseinate and soy protein acid gels(Elsevier, 2013-01-21) Ingrassia, Romina; Costa, Juan Pablo; Hidalgo, María Eugenia; Mancilla Canales, Manuel Arturo; Castellini, Horacio V.; Riquelme, Bibiana Doris; Risso, Patricia Hilda; Brandelli, AdrianoÍtem Acceso Abierto Estudio preliminar de los efectos de las radiaciones gamma sobre los glóbulos rojos humanos(Asociación Física Argentina, 2020-07) Estrada, Ezequiel; Castellini, Horacio V.; Acosta, Andrea; Di Tullio, Liliana; Borraz, Javier; Chinellato, Alejandro; Tack, Ivan; D’Arrigo, Mabel; Riquelme, Bibiana Doris; Galassi, Mariel ElisaÍtem Acceso Abierto In vitro alteration on erythrocytes mechanical properties by propofol, remifentanil and vecuronium(Elsevier, 2021-01-07) Alet, Analía I.; Batista da Silva, Marcus V.; Castellini, Horacio V.; Alet, Nicolás A.; Riquelme, Bibiana DorisÍtem Acceso Abierto Methods: A new protocol for in vitro red blood cell glycation(Elsevier, 2021-10-30) Batista da Silva, Marcus V.; Alet, Analía I.; Castellini, Horacio V.; Riquelme, Bibiana DorisÍtem Embargo New insights into the mechanics of erythrocytes: effects of radiation and several drugs of biomedical interest(Bulgarian Academy of Sciences, 2022) Riquelme, Bibiana Doris; Toderi, Martín A.; Batista, M.; Galassi, Mariel Elisa; Castellini, Horacio V.; Estrada, Ezequiel; Alet, Analía I.Ítem Acceso Abierto Preliminary study of alterations in human red blood cells by irradiation with high energy photons(Blucher, 2019) Riquelme, Bibiana Doris; Estrada, Ezequiel; Castellini, Horacio V.; Acosta, Andrea; Chinelatto, Alejandro; Tack, Ivan; Borraz, Javier; Di Tullio, Liliana; Galassi, Mariel Elisa; Sociedade Brasileira de Biofísica; D'Arrigo, Mabel. Colaboración en preparación de muestras biológicas; Castellani, Daniel. Colaboración en la fabricación del dispositivo adaptador de muestra.Introduction: Transfusion-associated graft-versus-host disease can be prevented by treating cellular blood products with gamma irradiation. A wide range of gamma irradiation dose levels are used in routine practice, but gamma irradiation dose of 25 Gy may be required to completely inactivate T cells in Red Blood Cells (RBC) units (Pelszynski, M. et al., 1994). This process decreases the survival of the RBC transfused, so it is crucial to understand the alterations caused by gamma irradiation to the erythrocyte membrane. In previous works, the biochemical and hematological effects of gamma irradiation at different storage periods were studied. It was observed that irradiation of the erythrocytes increases red cells hemolysis and leakage of intracellular potassium (Adams, F. et al., 2015; Yousuf, R. et al., 2018). The mechanisms through which irradiation causes the loss of RBC viability could be related to the primary effects of radiation. Gamma and X-ray Ionizing radiation cause indirect damage through the reactive oxygen species generated by water radiolysis (Anand, A.J. et al., 1997). The reduced deformability of RBC after irradiation could be related to the interaction of the oxygen-derived radicals with the membranes, affecting their mechanical properties and leading to deformability impairment (Kim, Y.-K. et al., 2008). In a recent work (AlZahrani K. et al., 2017), nanoestructural changes in the RBC membrane at different doses of gamma irradiation were observed using atomic force microscopy. The images shown that the roughness of the cell membrane increased dramatically with increasing doses, affecting their biophysical properties. However, more research is needed to understand the effects of gamma irradiation on the mechanical and adhesion properties of RBC. For this reason, in the present work we set out to measure the mechanical and aggregation parameters of human red blood cells exposed to gamma photons in different doses in order to determine the possible alterations due to radiation.Ítem Acceso Abierto Study of non-linear viscoelastic behavior of the human red blood cell(arXiv.org, 2018) Castellini, Horacio V.; Riquelme, Bibiana Doris