SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST - SITIO DE TEST

Examinando por Autor "Racca, Liliana"

Mostrando 1 - 3 de 3
  • Miniatura
    ÍtemAcceso Abierto
    Acute diarrhoea in children: determination of duration using a combined bismuth hydroxide gel and oral rehydration solution therapy vs. oral rehydration solution
    (MDPI, 2016-12-21) Oviedo, Adriana; Díaz, Mirna; Valenzuela, María Laura; Vidal, Victoria; Racca, Liliana; Bottai, Hebe; Priore, Graciela; Peluffo, Graciela; Di Bartolomeo, Susana; Cabral, Graciela; Toca, María del Carmen
    Oral rehydration salt (ORS) treatment in young children with acute diarrhoea (AD) has contributed to decrease mortality associated with dehydration although effective strategies to reduce morbidity associated with this disease are required. The aim of this study was to evaluate the diarrhoea duration when using combined colloidal bismuth hydroxide gel (CBHG) and oral rehydration salt treatment compared with ORS therapy in children with AD. We designed a double-blind, randomised prospective study with treatment and control groups. Patients aged one to 12 years, with no prior pathology and with AD of less than 48 h were included. The Chi-squared and Mann-Whitney tests were used, as well as the Cox proportional hazards model and the Kaplan-Meier estimator. Patients were randomised into an ORS and CBHG treatment group and a control group for ORS plus placebo. (Average age: 3.2 years). The result of the post-treatment evaluation with respect to the average duration of AD was 25.5 h for the treated group vs. 41.5 h for the control group (p = 0.015). The average number of stools was 4.8 in the treated group and 8.2 in the control group (p = 0.032). We conclude that the use of CBHG plus ORS significantly reduced the duration of AD, the number of stools and the percentage of children with persistent AD after 24 h of treatment compared to the control group. AD remitted almost twice as fast in patients treated with CBHG and ORS compared to those who received ORS plus placebo.
  • Miniatura
    ÍtemAcceso Abierto
    Assessing endocrine and immune parameters in human immunodeficiency virus-infected patients before and after the immune reconstitution inflammatory syndrome
    (Brazilian Society of Endocrinology and Metabolism, 2018-02) Rateni, Liliana Beatriz; Lupo, Sergio; Racca, Liliana; Palazzi, Jorge; Ghersevich, Sergio
    Objective: The present study compares immune and endocrine parameters between HIV-infected patients who underwent the Immune Reconstitution Inflammatory Syndrome (IRIS-P) during antiretroviral therapy (ART) and HIV-patients who did not undergo the syndrome (non-IRIS-P). Materials and methods: Blood samples were obtained from 31 HIV-infected patients (15 IRIS-P and 16 non-IRIS-P) before ART (BT) and 48 ± 2 weeks after treatment initiation (AT). Plasma Interleukin-6 (IL-6) and Interleukin-18 (IL-18) were determined by ELISA. Cortisol, dehydroepiandrosterone sulfate (DHEA-S) and thyroxin concentrations were measured using chemiluminescence immune methods. Results: Concentrations of IL-6 (7.9 ± 1.9 pg/mL) and IL-18 (951.5 ± 233.0 pg/mL) were significantly higher (p < 0.05) in IRIS-P than in non-IRIS-P (3.9 ± 1.0 pg/mL and 461.0 ± 84.4 pg/mL, respectively) BT. Mean T4 plasma level significantly decreased in both groups of patients after treatment (p < 0.05). In both groups cortisol levels were similar before and after ART (p > 0.05). Levels of DHEA-S in IRIS-P decreased AT (1080.5 ± 124.2 vs. 782.5 ± 123.8 ng/mL, p < 0.05) and they were significantly lower than in non-IRIS-P (782.5 ± 123.8 vs. 1203.7 ± 144.0 ng/mL, p < 0.05). IRIS-P showed higher values of IL-6 and IL-18 BT and lower levels of DHEA-S AT than in non-IRIS-P. Conclusion: These parameters could contribute to differentiate IRIS-P from non-IRIS-P. The significant decrease in DHEA-S levels in IRIS-P after ART might suggest a different adrenal response
  • Miniatura
    ÍtemAcceso Abierto
    Parasitosis intestinales en una población pediátrica de la ciudad de Rosario, Santa Fe, Argentina
    (Federación Bioquímica de la Provincia de Buenos Aires, 2011-04) Indelman, Paula; Echenique, Claudia G.; Bertorini, Griselda; Racca, Liliana; Gomez, Carlos; Luque, Alicia Graciela; Magaró, Hortensia María
    Las parasitosis intestinales afectan principalmente a los niños. El objetivo de este trabajo es conocer la situación actual en una población pediátrica de diferentes zonas de la ciudad de Rosario, Santa Fe (Argentina) y comparar la prevalencia parasitaria con estudios similares realizados en los períodos 1983/1984, 1990/1991, 1992/1993 y 2007/2008. Se recolectaron muestras de materia fecal por deposición espontánea de 112 pacientes, 51 niñas y 61 niños, con edades comprendidas entre 4 meses y 16 años, provenientes de 10 Centros de Atención Primaria de la Salud (Secretaría de Salud Pública - Municipalidad de Rosario). Las muestras fueron sometidas a examen macroscópico y microscópico directo y a métodos de concentración. En el período 2007/2008 los parásitos más hallados fueron Blastocystis hominis, Giardia lamblia y Ascaris lumbricoides. La prevalencia parasitaria disminuyó del 50% al 41%. Blastocystis hominis aumentó a través del tiempo; Giardia lamblia mantuvo valores constantes en las cuatro etapas; Entamoeba coli disminuyó en los últimos 14 años y Ascaris lumbricoides aumentó significativamente en relación con el período 1983/1984. Disminuyeron los individuos poliparasitados y aumentaron los monoparasitados con respecto a años anteriores. La disminución de las enteroparasitosis podría deberse a políticas de saneamiento ambiental, campañas de prevención y desparasitación realizadas desde los distintos efectores de salud municipales.