Characterisation of ST25 NDM-1-producing Acinetobacter spp. strains leading the increase in NDM-1 emergence in Argentina

Carbapenem-resistant Acinetobacter baumannii are recognised by the US Centers for Disease Control and Prevention (CDC) as an urgent threat [1]. The most prevalent mechanism of carbapenem resistance in Acinetobacter spp. is due to the presence of carbapenem-hydrolysing class D β-lactamases, with OXA-23 being the most common. The observed dispersion of blaOXA-23 is attributed in part to the spread of successful A. baumannii global clones such as GC1 and GC2 [2]. However, in the most recent years an increased emergence of blaNDM-1-harbouring Acinetobacter spp. isolates has been reported