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Analysis of the genetic diversity and phylogenetic relationships of putative human papillomavirus types

dc.citation.titleJournal of General Virology
dc.citation.volume94(Pt 11)
dc.creatorChouhy, Diego
dc.creatorBolatti, Elisa María
dc.creatorPerez, Germán Roberto
dc.creatorGiri, Adriana Angélica
dc.date.accessioned2017-12-06T12:13:09Z
dc.date.available2017-12-06T12:13:09Z
dc.date.issued2013-11
dc.descriptionMore than 170 human papillomavirus (HPV) types have been completely sequenced, curated and divided into five genera: Alphapapillomavirus, Betapapillomavirus, Gammapapillomavirus, Mupapillomavirus and Nupapillomavirus. With the application of PCR methods, hundreds of putative novel HPV types have been identified as PCR amplicons in mucosa and skin. However, at present there are no studies reporting a systematic search of the currently known L1 amplicons and their phylogenetic relationships. This survey revealed the existence of at least 202 different putative HPV types that are pending for full-genome characterization: five alphapapillomaviruses, 37 betapapillomaviruses, 159 gammapapillomaviruses and one mupapillomavirus. All potential viruses of the genera Alphapapillomavirus and Betapapillomavirus were grouped in the defined species, while 59 putative gammapapillomaviruses types were segregated in 21 unidentified putative species. These data highlight the need for progress in the identification of additional taxa of the family Papillomaviridae in order to elucidate the diversity, evolution and medical implications of these viruses.es
dc.description.filFil: Chouhy, Diego. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.description.filFil: Chouhy, Diego. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.description.filFil: Bolatti, Elisa María. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.description.filFil: Germán R. Pérez. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.description.filFil: Germán R. Pérez. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.description.filFil: Giri, Adriana Angélica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Area Virología; Argentina
dc.description.filFil: Giri, Adriana Angélica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario (UNR-CONICET); Argentina
dc.description.sponsorshipAgencia Nacional de Promoción Científica y Tecnológica (Proyectos PICT 2008-0421 y PICT 2012-0652)es
dc.formatapplication/pdf
dc.format.extent2480-2488
dc.identifier.other0022-1317
dc.identifier.otherhttps://dx.doi.org/10.1099/vir.0.055137-0
dc.identifier.urihttp://hdl.handle.net/2133/9862
dc.language.isoenges
dc.relation.publisherversionhttps://dx.doi.org/10.1099/vir.0.055137-0es
dc.relation.publisherversionhttp://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.055137-0es
dc.rightsopenAccesses
dc.rights.holderMicrobiology Societyes
dc.rights.holderChouhy, Diegoes
dc.rights.holderBolatti, Elisa Maríaes
dc.rights.holderPérez, Germán R.es
dc.rights.holderGiri, Adriana Angélicaes
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ar/*
dc.subjectHuman papillomaviruses
dc.subjectPutative typeses
dc.subjectDiversityes
dc.titleAnalysis of the genetic diversity and phylogenetic relationships of putative human papillomavirus typeses

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