(FBIOyF) Departamento de Ciencias de los Alimentos y del Medio Ambiente - Artículo de Revista
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Item type: Ítem , Access status: Acceso Abierto , Characterization of polyphenols compounds extracted from stressed apple peel and their interaction with β-lactoglobulin(Elsevier, 2023-11) Llopart, Emilce E.; Verdini, Roxana Andrea; Delorenzi, Néstor Jorge; Busti, Pablo AndrésThis paper proposes to apply a postharvest environmental stress to red apples, Malus domestica, variety Red Delicious in order to increase the polyphenols compounds (PP) content in their peels. The possibility of enhancing extractable PP provides a useful alternative for the use of discarded crops in the food industry. A great increase in PP was observed in response to light damage produced by the environmental stress applied in this work. Flavonols > anthocyanins > flavanols > dihydrochalcones > phenolic acids is the order in PP content. The interaction of the extracted PP from unstressed and stressed apple peels with beta-lactoglobulin (β-LG) was characterized. A PP/β-LG complex which was formed with one single binding site in the protein was determined. The interaction was spontaneous and enthalpy driven. PP extracted from unstressed samples had greater affinity for the protein than PP extracted from stressed samples, possibly due to the polar characteristic of anthocyanins. The results of this last study could provide a better understanding of the interaction between PP and β-LG to incorporate them into functional foods.Item type: Ítem , Access status: Acceso Abierto , WNT signaling in neuronal maturation and synaptogenesis(Frontiers Media, 2013-07-04) Rosso, Silvana Beatriz; Inestrosa, Nibaldo C.The Wnt signaling pathway plays a role in the development of the central nervous system and growing evidence indicates that Wnts also regulates the structure and function of the adult nervous system. Wnt components are key regulators of a variety of developmental processes, including embryonic patterning, cell specification, and cell polarity. In the nervous system, Wnt signaling also regulates the formation and function of neuronal circuits by controlling neuronal differentiation, axon outgrowth and guidance, dendrite development, synaptic function, and neuronal plasticity. Wnt factors can signal through three very well characterized cascades: canonical or β-catenin pathway, planar cell polarity pathway and calcium pathway that control different processes. However, divergent downstream cascades have been identified to control neuronal morphogenesis. In the nervous system, the expression of Wnt proteins is a highly controlled process. In addition, deregulation of Wnt signaling has been associated with neurodegenerative diseases. Here, we will review different aspects of neuronal and dendrite maturation, including spinogenesis and synaptogenesis. Finally, the role of Wnt pathway components on Alzheimer’s disease will be revised.Item type: Ítem , Access status: Acceso Abierto , Milk improved the metabolic syndrome in obese β rats(Fundación Revista Medicina (Buenos Aires), 2014) Olguín, María Catalina; Posadas, Marta D.; Revelant, Gilda C.; Marinozzi, Darío O.; Labourdette, Verónica B.; Zingale, María Isabel; Venezia, María Rosa; Wiener Lab; La Sibila S.A.The response of adult spontaneously obese rats from the IIMb/Beta strain fed a high calcium skimmed milk diet (MHCa), high calcium from carbonate (HCa) and a normal AIN 93 diet during 45 days was evaluated. Body weight, food intake and fecal fat excretion were measured. At the end of the experiment rats were euthanized, abdominal fat pads and livers were excised and weighed. Blood and liver triacylglycerols, total cholesterol and fractions were quantified. Body weight increase and abdominal fat pads in the MHCa group were significantly lower than in the other two. Plasma triacylglycerols, total and LDL-cholesterol were diminished in the MHCa group. Fecal lipid excretion was increased in the adult MHCa group. Total liver lipids and triacylglycerols showed a significant diminution in the MHCa group. These results suggest that calcium and other bioactive compounds from milk, most probably present in whey fraction, and not calcium carbonate exerted an "anti-obesity" effect on these rats.Item type: Ítem , Access status: Embargo , Levels and patterns of substance use among school-attending adolescents in Rosario (Santa Fe - Argentina) during 2016, 2018 and 2019(Taylor and Francis, 2023-07-05) Biolatto, Silvana; Konjuh, Cintia; Drogo, Claudia; Pacchioni, AlejandraItem type: Ítem , Access status: Acceso Abierto , Uso de sustancias psicoactivas en estudiantes de escuelas secundarias de Rosario (Argentina)(Asociación Toxicológica Argentina, 2020-09) Biolatto, Silvana M.; Drogo, Claudia; Pardal, María Alejandra; Bottai, Hebe; Reinoso, Amelia; Pacchioni, Alejandra MaríaItem type: Ítem , Access status: Acceso Abierto , Sono-Enzymatically Embedded Antibacterial Silver-Lignin Nanoparticles on Cork Filter Material for Water Disinfection(MDPI, 2022-10-02) Bermeo, Lizeth; Ivanova, Kristina; Pérez, Leonardo Martín; Forés, Eva; Pérez Rafael, Silvia; Casas Zapata, Juan C.; Morató, Jordi; Tzanov, TzankoItem type: Ítem , Access status: Acceso Abierto , Effects of 2,4-dichlorophenoxyacetic acid on the ventral prostate of rats during the peri-pubertal, pubertal and adult stage(Taylor and Francis, 2016-01) Pochettino, Arístides A.; Hapon, María Belén; Biolatto, Silvana M.; Madariaga, María José; Jahn, Graciela A.; Konjuh, Cintia N.Item type: Ítem , Access status: Acceso Abierto , Aqueous Extract of Prosopis strombulifera (LAM) BENTH Induces Cytotoxic Effects against Tumor Cell Lines without Systemic Alterations in BALB/c Mice(OMICS Publishing Group, 2014-12-31) Hapon, María Belén; Hapon, María Vanda; Persia, Andres; Pochettino, Arístides A.; Lucero, Gabriela Susana; Gamarra-Lúques, C.Item type: Ítem , Access status: Acceso Abierto , Insecticidal activity of volcanic ash against Sitophilus oryzae L. (Coleoptera: Curculionidae) under laboratory conditions(Asociación Argentina de Ecología, 2014-04) Buteler, Micaela; López García, Guillermo P.; Pochettino, Arístides A.; Stefanazzi, Natalia; Ferrero, Adriana A.; Stadler, TeodoroItem type: Ítem , Access status: Acceso Abierto , Physicochemical characterization of a heat treated calcium alginate dry film prepared with chicken stock(Wiley, 2017-02-20) Báez, Germán David; Piccirilli, Gisela Noemí; Ballerini, Griselda A.; Frattini, Agustín; Busti, Pablo Andrés; Verdini, Roxana Andrea; Delorenzi, Néstor Jorge; The chicken stock used in this work was prepared by Chef Damian Delorenzi.Item type: Ítem , Access status: Acceso Abierto , Effect of freezing on physical properties of whey protein emulsion films(Elsevier, 2013-06) Soazo, Marina del Valle; Pérez, Leonardo Martín; Rubiolo, Amelia Catalina; Verdini, Roxana AndreaItem type: Ítem , Access status: Acceso Abierto , Effect of pH on the effectiveness of whey protein/glycerol edible films containing potassium sorbate to control non-O157 shiga toxin-producing Escherichia coli in ready-to-eat foods(Elsevier, 2014-03) Pérez, Leonardo Martín; Soazo, Marina del Valle; Balagué, Claudia Elizabeth; Rubiolo, Amelia Catalina; Verdini, Roxana AndreaItem type: Ítem , Access status: Acceso Abierto , Prefreezing application of whey protein-based edible coating to maintain quality attributes of strawberries(Wiley, 2015-03) Soazo, Marina del Valle; Pérez, Leonardo Martín; Rubiolo, Amelia Catalina; Verdini, Roxana AndreaItem type: Ítem , Access status: Acceso Abierto , Antimicrobial and physicochemical characterization of whey protein concentrate edible films incorporated with liquid smoke.(Elsevier, 2016-10) Soazo, Marina del Valle; Pérez, Leonardo Martín; Piccirilli, Gisela Noemí; Delorenzi, Néstor Jorge; Verdini, Roxana AndreaItem type: Ítem , Access status: Acceso Abierto , Heat treatment of calcium alginate films obtained by ultrasonic atomizing: physicochemical characterization(Elsevier, 2015-10) Soazo, Marina del Valle; Báez, Germán David; Barboza, Andrea; Busti, Pablo Andrés; Rubiolo, Amelia Catalina; Verdini, Roxana Andrea; Delorenzi, Néstor JorgeItem type: Ítem , Access status: Acceso Abierto , Effect of different combinations of glycerol and/or trehalose on physical and structural properties of whey protein concentrate-based edible films(Elsevier, 2016-05) Pérez, Leonardo Martín; Piccirilli, Gisela Noemí; Delorenzi, Néstor Jorge; Verdini, Roxana AndreaItem type: Ítem , Access status: Acceso Abierto , Are Changes in the Wnt/β-Catenin Pathway Involved in Cocaine and Stress-Induced Long-Term Neuroadaptations?(Elyns Group, 2017-10-03) Cuesta, Santiago; Pacchioni, Alejandra María; Cerchiara, Florencia: for their English technical assistanceItem type: Ítem , Access status: Acceso Abierto , Role of Wnt/beta-catenin pathway in the nucleus accumbens in long-term cocaine-induced neuroplasticity : a possible novel target for addiction treatment(Wiley, 2016-12-07) Cuesta, Santiago; Batuecas, Jorgelina; Severin, María Julia; Funes, Alejandrina; Rosso, Silvana Beatriz; Pacchioni, Alejandra MaríaItem type: Ítem , Access status: Acceso Abierto , Wnt/beta-catenin pathway in the prefrontal cortex is required for cocaine-induced neuroadaptations(Wiley, 2017-07) Cuesta, Santiago; Severin, María Julia; Batuecas, Jorgelina; Rosso, Silvana Beatriz; Pacchioni, Alejandra María